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gamma Synuclein Rabbit anti-Human, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA118263

Catalog No. 01-670-516


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Description

Description

Synuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkinson's PD) and breast cancer. In AD, a peptide derived from alpha synuclein forms an intrinsic component of plaque amyloid. In PD, an alpha synuclein accumulates in Lewy bodies. An allele of alpha synuclein has been linked to many familial cases of PD. In breast cancer increased expression of gamma synuclein correlates with the disease progression. Synucleins appear to be involved in the membrane plasticity in developing song control system of songbirds.

PA1-18263 detects gamma Synuclein from human and rat samples.PA1-18263 has been successfully used in Western blot procedures.The PA1-18263 immunogen is a synthetic peptide corresponding to residues E(114) K E E V A E E A Q S G G D(127) of human gamma synuclein protein, conjugated to diphteria toxid.Reconstitute with 100 ul of distilled water.
Specifications

Specifications

gamma Synuclein
Polyclonal
whole serum with no preservative
O76070, Q63544
Persyn, Breast cancer-specific gene 1 protein, Synoretin, SR
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Rat
Western Blot
Unconjugated
SNCG
Lyophilized
SNCG
Synthetic peptide corresponding to residues E(114) K E E V A E E A Q S G G D(127) of human gamma synuclein protein.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
64347, 6623
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