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gamma Tubulin Mouse anti-Bovine, Chicken, Human, Mouse, Plant, Porcine, Protozoa, Rat, Clone: TU-30, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA119421

Catalog No. 01-676-167


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Description

Description

This antibody recognizes the C-terminal peptide sequence EYHAATRPDYISWGTQ (aa 434-449) of gamma-tubulin.

The gamma-tubulin (TUBG1; relative molecular weight about 48 kDa) is a minor member of tubulin family (less that 0.01% of tubulin dimer). The gamma-tubulin ring structures, however, serve to provide structural primer for initiation of microtubular nucleation and growth, thereby being crutial for microtubule-based cellular processes, above all for mitotic spindle formation. In animal cells, a center of microtubule organization is the centrosome composed of a pair of cylindrical centrioles surrounded by fibrous pericentriolar material containing gamma-tubulin. Formation of the mitotic spindle is preceded by duplication of centrosome during S phase. Before mitosis, both centrosomes increase their microtubule nucleation capacity and form two microtuble asters that are pushed apart from each other by the forces of motor proteins associated at the microtubule surface.
Specifications

Specifications

gamma Tubulin
Monoclonal
1 mg/mL
PBS with 15mM sodium azide; pH 7.4
Q0VCD2, P23258, P83887, P83888
centrosome marker
Mouse
IgG1
100 μg
4° C, do not freeze
Primary
103733, 106505426, 252921, 420025, 541101, 7283
Immunocytochemistry, Immunofluorescence, Western Blot
TU-30
Unconjugated
TUBG1
Liquid
TUBG1
C-terminal peptide of gamma-Tubulin counjugated to KLH.
Protein A
RUO
Antibody
Monoclonal
Bovine, Chicken, Human, Mouse, Plant, Porcine, Protozoa, Rat
Documents
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