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GATA3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520892

Catalog No. PIPA520892


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Description

Description

A suggested positive control is human brain tissue lysate. PA5-20892 can be used with blocking peptide PEP-1006.

GATA3 is a zinc finger transcription factor that was first recognized as a possible determit of T cell development. Later studies demonstrated that it is expressed in trophoblast giant cells and regulates trophoblast-specific genes during development. Specifically, GATA3 is selectively expressed in the trophectoderm of the peri-implantation embryo and regulates CDX2, which is required for the transcriptional repression of the POU5F1/Oct4 and NANOG genes and is thus essential for the segregation of the inner cell mass and trophectoderm at the blastocyst stage. Decreased or null-expression expression of GATA3 has also been suggested to play a major role in the development and progression of luminal breast cancer.
Specifications

Specifications

GATA3
Polyclonal
Unconjugated
GATA3
Liquid
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
14462, 2625, 85471
ChIP assay, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P23771, P23772
GATA3
A 17 amino acid peptide near the carboxy terminus of human GATA3.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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