MilliporeSigma™ anti-GBA Clone: 200,
Mouse Monoclonal Antibody
Manufacturer: MilliporeSigma™ AP1140100UG
Specifically detects GBA Clone: 200 in Human samples, and it is validated for ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immuno BlottingAcid beta-glucosidase (GBA) is a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. It catalyzes the breakdown of the glycolipid glucosylceramide to ceramide and glucose. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides.
|ELISA, Immunoblot, Immunoblot, Immunocytochemistry, Immunohistochemistry (Paraffin)|
|In PBS, pH 7.2.|
|A recombinant polypeptide corresponding to amino acids of 146-236 human GBA, expressed as a GST fusion protein|
|Recognizes the ∽60kDa GBA protein in MCF-7 and HeLa cells and human breast cancer tissue.|
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