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MilliporeSigma™ anti-GBA Clone: 200,
Mouse Monoclonal Antibody
Supplier: MilliporeSigma™ AP1140100UG
Description
Specifically detects GBA Clone: 200 in Human samples, and it is validated for ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immuno Blotting
Acid beta-glucosidase (GBA) is a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. It catalyzes the breakdown of the glycolipid glucosylceramide to ceramide and glucose. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides.Specifications
| GBA | |
| Monoclonal | |
| Unconjugated | |
| Mouse | |
| 100 μg | |
| Primary | |
| Human | |
| Purified |
| ELISA, Immunoblot, Immunoblot, Immunocytochemistry, Immunohistochemistry (Paraffin) | |
| 200 | |
| In PBS, pH 7.2. | |
| A recombinant polypeptide corresponding to amino acids of 146-236 human GBA, expressed as a GST fusion protein | |
| RUO | |
| Recognizes the ∽60kDa GBA protein in MCF-7 and HeLa cells and human breast cancer tissue. | |
| −20°C | |
| IgG2a |
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