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GDNF Chicken anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Chicken Polyclonal Antibody

Manufacturer:  Invitrogen PA19524

Catalog No. 01-674-407


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Description

Description

PA1-9524 detects GDNF in human, mouse and rat samples. PA1-9524 has been successfully used in Western blot, ELISA, and Immunohistochemistry procedures. By Western blot, PA1-9524 detects a 24 kDa protein representing GDNF. PA1-9524 immunogen is a synthetic peptide based on the human GDNF protein. Store product at 4°C for up to one week, and -20°C for long term storage.

GDNF is a glycosylated, disulfide-bonded homodimer molecule. It was first discovered as a potent survival factor for midbrain dopaminergic neurons and was then shown to rescue these neurons in animal models of Parkinson ft.s disease. GDNF is about 100 times more efficient survival factor for spinal motor neurons than the neurotrophins. GDNF is a neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
Specifications

Specifications

GDNF
Polyclonal
Unconjugated
GDNF
Liquid
GDNF
Synthetic peptide based on the human GDNF protein.
IgY fraction
RUO
Antibody
Polyclonal
Human, Mouse, Rat
ELISA, Immunohistochemistry, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
P39905, P48540, Q07731
Glial cell line-derived neurotrophic factor, Astrocyte-derived trophic factor 1, ATF1, ATF2, HFB1-GDNF
Chicken
IgY
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
14573, 25453, 2668
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