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Gemin 2 Mouse anti-Human, Xenopus laevis, Clone: 2E17, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA15777

Catalog No. 01-674-891


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Description

Description

MA1-5777 detects Gemin2 in human and xenopus samples. MA1-5777 has been successfully used in Western blot, immunoprecipitation, immunofluorescence and ELISA procedures. MA1-5777 detects a band of approximately 34 kDa. The MA1-5777 immunogen is His-Gemin2 (starting at 2nd methionine). Store at 4°C for one month, or in small aliquots at -20°C for longer periods.

This gene encodes one of the proteins found in the SMN complex, which consists of the suvival of motor neuron protein and several gemin proteins. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.
Specifications

Specifications

Gemin 2
Monoclonal
1 mg/mL
PBS with 0.1% sodium azide
O14893
GEMIN2, SIP1-delta
Mouse
IgG1
100 μL
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Primary
494588, 8487
ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
2E17
Unconjugated
GEMIN2
Liquid
GEMIN2, gemin2.S
His-Gemin2 (starting at 2nd methionine) from SP2/0 cells
Protein A
RUO
Antibody
Monoclonal
Human, Xenopus laevis
Documents
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