Gemin 2 Mouse anti-Human, Xenopus laevis, Clone: 2E17, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA15777
This gene encodes one of the proteins found in the SMN complex, which consists of the suvival of motor neuron protein and several gemin proteins. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. This protein interacts directly with the survival of motor neuron protein and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration.MA1-5777 detects Gemin2 in human and xenopus samples.MA1-5777 has been successfully used in Western blot, immunoprecipitation, immunofluorescence and ELISA procedures. MA1-5777 detects a band of approximately 34 kDa.The MA1-5777 immunogen is His-Gemin2 (starting at 2nd methionine).Store at 4ºC for one month, or in small aliquots at -20ºC for longer periods.
|PBS with 0.1% sodium azide|
|Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|ELISA, Immunofluorescence, Immunoprecipitation, Western Blot|
|His-Gemin2 (starting at 2nd methionine) from SP2/0 cells|
|Human, Xenopus laevis|
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