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GFR alpha-1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA132476

Catalog No. PIPA132476


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Description

Description

PA1-32476 detects GFR alpha 1 from human, rat, mouse samples. PA1-32476 has been successfully used in Western blot applications. The PA1-32476 immunogen is: Synthetic peptide: TALRVKNKPLGPAG, corresponding to amino acids 369-382 of Human GFR alpha 1.

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.
Specifications

Specifications

GFR alpha-1
Polyclonal
Unconjugated
GFRA1
Liquid
GFRA1
synthetic peptide TALRVKNKPLGPAG, corresponding to amino acids 369-382 of Human GFR alpha 1.
IgG fraction
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
0.5 mg/mL
PBS with 0.02% sodium azide
P56159, P97785, Q62997
DKFZp313E1012, DKFZp686J0156, FLJ10561, FLJ31546, GDNFR, GDNFRA, GFR-ALPHA-1, MGC23045, RET1L, RETL1, TRNR1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
14585, 25454, 2674
Documents
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