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GHRHR Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA3117

Catalog No. PA3117


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Description

Description

PA3-117 detects GHRH-R in human samples. PA3-117 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry procedures. By Western blot, this antibody detects an ~40 kDa protein representing GHRH-R in human samples. In immunohistochemistry, GHRH-R immunoreactivity is predomitly localized at the plasma membrane. The PA3-117 immunizing peptide corresponds to amino acid residues 403-422 from human GHRH-R.

Growth Hormone Releasing Hormone (GHRH) is a member of a family of peptide hormones that also includes VIP (vasoactive intestinal polypeptide) and PACAP (pituitary adenylate cyclase-activating polypeptide). It is a hypothalamic peptide that binds to G-protein coupled receptors to stimulate secretion and synthesis of growth hormone (GH). GHRH receptor proteins have been identified on the plasma membrane of primary human tumor cells, and are thought to be involved in the growth of a variety of cancer cells.
Specifications

Specifications

GHRHR
Polyclonal
whole serum with 0.05% sodium azide
Q02643
Growth Hormone Releasing Hormone Receptor
Rabbit
IgG
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
GHRHR
Liquid
GHRHR
Synthetic peptide, KLH conjugated, corresponding to residues R(403) T R A K W T T P S R S A A K V L T S M(422) of human GHRH-R.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2692
Documents
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