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GLI1 Rabbit anti-Human, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523411

Catalog No. PIPA523411


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Description

Description

GLI1 is a protein originally isolated in human glioblastoma. The GLI proteins are the effectors of Sonic Hedgehog (Hh) signaling and have been shown to be involved in cell-fate determination, proliferation and patterning in many cell types and most organs during embryo development. GLI1 was originally isolated from a glioma tumour and has been found to be up regulated in many tumors including muscle, brain and skin tumors such as Basal cell carcinoma (BCC). Shh and the Gli genes are normally expressed in hair follicles, and skin tumours expressing Gli1 may arise from hair follicles. The level of Gli1 expression correlates with the tumor grade in bone and soft tissue sarcomas.
Specifications

Specifications

GLI1
Polyclonal
Unconjugated
GLI1
Liquid
GLI1
Synthetic peptide (954 PNLPNHKSGSYPTPSPC 970) of GLI1 protein.
Protein A
RUO
Antibody
Polyclonal
Human, Non-human Primate
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 0.05% sodium azide
P08151
GLI, glioma-associated oncogene 1, glioma-associated oncogene homolog 1 (zinc finger protein), oncogene GLI, zinc finger protein GLI1
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
2735
Documents
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