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GLI3 Rabbit anti-Human, Mouse, Xenopus laevis, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA129595

Catalog No. PA129595


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Description

Description

PA1-29595 detects Gli3 from human samples. Expected to cross react with chicken (100% identity), human (100% identity), mouse, (94% identity), Xenopus laevis (100% identity) due to sequence homology. PA1-29595 has been successfully used in immunohistochemistry (frozen tissue), Western blot, and ELISA applications. The PA1-29595 immunogen is Synthetic peptide: NEDESPGQTYHRERRNA-C conjugated to KLH, corresponding to amino acids 41-57 of Human GLI3. Store at 4°C. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
Specifications

Specifications

Gli3
Polyclonal
Unconjugated
GLI3
Liquid
GLI3, gli3.L
synthetic peptide NEDESPGQTYHRERRNA-C conjugated to KLH, corresponding to amino acids 41-57 of Human GLI3.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Xenopus laevis
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
P10071, Q61602, Q91660
ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV
Rabbit
IgG
50 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
14634, 2737, 397837
Documents
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