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ZGLP1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA525414

Catalog No. PIPA525414

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Glucagon is initially synthesised as proglucagon, which is 180 amino acids in length and is cleaved proteolytically. It contains a region corresponding to Glucagon itself, in addition to a signal peptide, spacer regions and two Glucagon-like peptide sequences. GLP1 is encoded by the fourth exon of the six in the human Glucagon gene. It is 37 amino acids in length and has 48% amino acid sequence homology to Glucagon, and is thought to have arisen by gene duplication. The sequence of GLP1 is conserved across many species, however, indicating that it has a particular function. GLP1 is a potent insulin secretagogue, renders pancreatic beta cells  ft.glucose-competent ft. and may be useful in the treatment of diabetes mellitus.
Specifications

Specifications

ZGLP1
Polyclonal
Unconjugated
ZGLP1
Liquid
ZGLP1
KLH conjugated synthetic peptide between 85-112 amino acids from the central region of human GLP1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Flow Cytometry, Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide
P0C6A0
GLP-1, GLP1, GATA like protein 1, GATA like protein-1, GATA-like protein 1, GATA-type zinc finger protein 1
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
100125288
Documents
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