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Glucocorticoid Receptor Sheep anti-Human, Non-human primate, Polyclonal, Invitrogen™

Sheep Polyclonal Antibody

Manufacturer:  Invitrogen PA110856

Catalog No. 01-671-897


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Description

Description

PA1-10856 detects Glucocorticoid Receptor from human, and monkey samples. PA1-10856 has been successfully used in Western blot applications. The PA1-10856 immunogen is a synthetic peptide, conjugated to diphtheria toxoid, corresponding to residues 150-175 of squirrel monkey glucocorticoid receptor.

Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Glucocorticoids are a family of steroids necessary for the regulation of energy metabolism and the immune and inflammatory responses. These compounds exert their effect through their interaction with the glucocorticoid receptor (GR) and that complex ft.s subsequent association with DNA. All normal mammalian tissues examined to-date have been shown to contain glucocorticoid receptor. The corresponding gene for the glucocorticoid receptor is NR3C1.
Specifications

Specifications

Glucocorticoid Receptor
Polyclonal
whole serum with no preservative
P04150
GR, GCCR, GCR, Glucocorticoid receptor lymphocyte, GRL, Grl1, NR3C1, Nuclear receptor subfamily 3 group C member 1
Sheep
IgG
RUO
Antibody
Polyclonal
Human, Non-human Primate
Western Blot
Unconjugated
NR3C1
Liquid
NR3C1
Synthetic peptide corresponding to residues 150-175 of squirrel monkey glucocorticoid receptor, conjugated to diphtheria toxoid.
200 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2908
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