GLUT4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523052
This antibody is predicted to react with rat based on 100% sequence homology.Glucose Transporter 4 (GLUT4/SLC2A4) is a member of a family of proteins that facilitate glucose transport. In response to insulin GLUT4 translocates from low density microsomes to the plasma membrane. Activation of phosphatidylinositol-3-OH kinase is required for this trafficking event but is not sufficient. Insulin resistant subjects with and without diabetes show abnormal accumulation of GLUT4 in a dense membrane compartment in muscle and adipocytes from which insulin is unable to recruit GLUT4 to the cell surface.
|A synthetic peptide made to an internal portion of the human GLUT4 protein (between residues 480-509)|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.02% sodium azide|
|P14672, P14142, P19357|
|GLUT4, GLUT-4, glucose transporter type 4, insulin-responsive, insulin-responsive glucose transporter type 4, solute carrier family 2, facilitated glucose transporter member 4|
|-20°C or -80°C if preferred|
|20528, 25139, 6517|
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