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GluR1, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA137775

Catalog No. 01-673-514


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Description

Description

Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR1-7, NMDA1-3, KAI-2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.

Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is brain tissue.
Specifications

Specifications

GluR1
Polyclonal
TBS with 1% BSA and <0.1% sodium azide; pH 7.6
P42261
Glutamate Receptor 1
Rabbit
IgG
7mL
4° C, do not freeze, do not freeze
Primary
2890
Immunohistochemistry (Paraffin)
Unconjugated
GRIA1
Liquid
GRIA1
Synthetic peptide from C-terminus of human GluR1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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