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mGluR1 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA138130

Catalog No. 01-673-679


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Description

Description

This antibody is predicted to react with monkey, chicken, mouse, and rat based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is brain tissue.

Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR1-7, NMDA1-3, KAI-2) which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.
Specifications

Specifications

mGluR1
Polyclonal
PBS with 1% BSA and <0.1% sodium azide
Q13255, P97772
GPRC1A, GRM1A, MGLUR1, MGLUR1A, mGlu1, metabotropic glutamate receptor 1
Rabbit
IgG
1 mL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
2911, 14816
Immunohistochemistry (Paraffin)
Unconjugated
GRM1
Liquid
GRM1
Synthetic peptide from C-terminus of human mGluR1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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