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GluR2/GluR3 Rabbit anti-Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14660

Catalog No. PA14660


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Description

Description

This antibody is predicted to react with chicken, human, mouse and zebrafish based on 100% sequence homology. This antibody is specific for the ~100 kDa GluR2/3 protein.

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5 -methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990; Hollmann and Heinemann, 1994). The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003).
Specifications

Specifications

GluR2/GluR3
Polyclonal
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
P19491, P19492
Glutamate receptor 2, GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2, GRIA2, GLUR2
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
29627, 29628
Western Blot
Unconjugated
Gria3
Liquid
GRIA2, GRIA3
Synthetic peptide corresponding to the C-terminal region of rat GRIA2/3 conjugated to KLH
Affinity chromatography
RUO
Antibody
Polyclonal
Rat
Documents
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