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GluR2 Rabbit anti-Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14659

Catalog No. PA14659


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Description

Description

This antibody is predicted to react with chicken, human, mouse, non-human primate and zebrafish based on 100% sequence homology. This antibody is specific for the ~100 kDa GluR2 protein.

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5 -methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990; Hollmann and Heinemann, 1994). The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003).
Specifications

Specifications

GluR2
Polyclonal
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
P19491, P23819
Glutamate Receptor 2
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
29627, 14800
Western Blot
Unconjugated
Gria2
Liquid
GRIA2
Synthetic peptide corresponding to amino acid residues specific to rat GluR2 conjugated to KLH
Affinity chromatography
RUO
Antibody
Polyclonal
Rat
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