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GluR6/GluR7 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA137780

Catalog No. 01-673-519



Description

Description

This antibody is predicted to react with bovine, chicken, canine, amphibian, mouse, rabbit and rat based on sequence homology. Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 30 min at room temperature. A suggested positive control is brain tissue.

Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR1-7, NMDA1-3, KAI-2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.
Specifications

Specifications

GluR6/GluR7
Polyclonal
PBS with 1% BSA and <0.1% sodium azide; pH 7.6
Q13002, Q13003
GRIK2, GRIK3, EAA4, GLR6, MRT6, GLUK6, GLUR6, GluK2, Glutamate Receptor 6/7, Glutamate Receptor 6, Glutamate Receptor 7
Rabbit
IgG
1 mL
4° C, do not freeze
Primary
2898, 2899
Immunohistochemistry (Paraffin)
Unconjugated
GRIK3
Liquid
GRIK2, GRIK3
Synthetic peptide from C-terminus of human GluR6/7.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
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