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GLRA1/GLRA2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA184890

Catalog No. PA184890


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Description

Description

PA1-84890 detects a band at ~48 kDa in rat spinal cord lysates. Reconstitute with 0.1 mL PBS. For long term storage, the addition of 0.09% sodium azide is recommended. Prior to reconstitution, store at 4°C. After reconstitution, store undiluted at -20°C, avoiding freeze/thaw cycles. Rabbit anti glycine receptor recognizes an epitope within the N-terminal region (NT) of glycine receptor alpha 1 and alpha 2 subunits.

Glycine receptors are members of the ligand-gated ion channel superfamily, which mediate fast inhibitory neurotransmission. The receptors are pentameric membrane proteins which form chloride channels. Binding of glycine to its receptor produces an increase in chloride conductance and membrane hyperpolarisation. Four genes encoding glycine receptor alpha subunits have been identified, together with a single beta polypeptide. Each subunit consists of a large extracellular N-terminal region, four transmembrane domains, and a large cytoplasmic domain.
Specifications

Specifications

GLRA1/GLRA2
Polyclonal
Ammonium bicarbonate with no preservative
P23415, P23416, Q64018, Q7TNC8, P07727, P22771
GLRA1, Glra2, GLYRA1, Glycine receptor subunit alpha-1, Glycine receptor subunit alpha-2
Rabbit
IgG
200 μg
4° C
Primary
14654, 237213, 24397, 25674, 2741, 2742
Immunohistochemistry (Frozen), Western Blot
Unconjugated
GLRA2
Lyophilized
GLRA1, GLRA2
Synthetic peptide corresponding to the N-terminal region of rat glycine receptor alpha 1 subunit.
Affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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