HIV1 gp120 Rabbit anti-Virus, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA520488
PA5-20488 can be used with blocking peptide PEP-0608.Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
|Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C|
|PBS with 0.02% sodium azide|
|Human immunodeficiency virus; HIV Glycoprotein 120; HIV-1 Glycoprotein 120|
|16 amino acid peptide representing the major HIV-1 consensus sequence near the N-terminal region of V1/V2 loop.|
|Antigen affinity chromatography|
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