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HIV1 gp120 Rabbit anti-Virus, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA520488

Catalog No. PIPA520488


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Description

Description

PA5-20488 can be used with blocking peptide PEP-0608.

Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
Specifications

Specifications

HIV1 gp120
Polyclonal
Unconjugated
Liquid
Rabbit
IgG
100 μg
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Primary
Virus
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Human immunodeficiency virus; HIV Glycoprotein 120; HIV-1 Glycoprotein 120
16 amino acid peptide representing the major HIV-1 consensus sequence near the N-terminal region of V1/V2 loop.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Documents
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