Human gp130 Antibody, R&D Systems™

Mouse Monoclonal Antibody has been used in 1 publication

Supplier:  R&D Systems MAB628SP

Catalog No. MAB628SP

Description

gp130/CD130 Monoclonal specifically detects gp130/CD130 in Human samples. It is validated for Immunohistochemistry, Neutralization, ELISA Capture (Matched Antibody Pair).

Specifications

• Antigen: gp130/CD130
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: Lyophilized from a 0.2 μm filtered solution in PBS. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
• Gene Alias: CD130, CD130 antigen, CDw130, DKFZp564F053, gp130, gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form, IL-6 receptor subunit beta, IL-6R subunit beta, IL-6RB, IL-6R-beta, IL6ST, interleukin 6 signal transducer (gp130, oncostatin M receptor), interleukin receptor beta chain, interleukin-6 receptor subunit beta, Interleukin-6 signal transducer, Membrane glycoprotein 130, membrane glycoprotein gp130, Oncostatin-M receptor subunit alpha
• Host Species: Mouse
• Purification Method: Protein A or G purified from ascites
• Regulatory Status: RUO
• Gene ID (Entrez): 3572
• Reconstitution: Reconstitute at 0.5 mg/mL in sterile PBS.
• Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
• Isotype: IgG1

• Applications: Immunohistochemistry, Neutralization, ELISA
• Clone: 28105
• Dilution: Immunohistochemistry 5-25 ug/mL, Neutralization 0.02-0.1 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
• Gene Accession No.: P40189
• Gene Symbols: IL6ST
• Immunogen: Sf 21-derived recombinant human gp130 extracellular domain Leu24-Glu619 (Glu619-Asp, predicted) Accession # P40189
• Quantity: 25 μg
• Primary or Secondary: Primary
• Test Specificity: Detects human gp130 in ELISAs. In sandwich immunoassays, no significant cross-reactivity or interference with recombinant human (rh) CNTF, rhIL-6, rhIL-6 R, recombinant mouse (rm) IL-6, rhIL-11, rhLIF, rhLIF R, rmLIF, or rhOSM is observed. This antibody blocks the human gp130-mediated bioactivities induced by IL-6, IL-11, LIF, OSM, and CNTF.
• Target Species: Human
• Form: Purified

For Research Use Only