GPNMB Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA527874
PA5-27874 targets GPNMB in IHC (P) and WB applications and shows reactivity with Human samples. The PA5-27874 immunogen is recombit protein fragment corresponding to a region within amino acids 181 and 407 of Human GPNMB. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
|Recombit protein fragment corresponding to a region within amino acids 181 and 407 of Human GPNMB|
|Antigen affinity chromatography|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7|
|HGFIN, NMB, glycoprotein NMB, glycoprotein nmb-like protein, osteoactivin, transmembrane glycoprotein HGFIN, transmembrane glycoprotein NMB|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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