GSR Rabbit anti-Human, Yeast, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA523247
DescriptionGlutathione reductase (GSR or GR) is a crucial flavoenzyme in the antioxidant defense system that maintains high levels of reduced glutathione in the cytosol. It belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family and is a flavoprotein homodimer of two equal subunits with one mole of noncovalently bound FAD in each subunit. GR reduces glutathione disulphide (GSSG) to the sulfhydryl form (GSH) which is an important cellular oxidant and is used by glutathione peroxidase to detoxify hydrogen peroxide. Apart from NADPH, GR also uses FAD as a cofactor for the process. In sperm, GR and glutathione peroxidase function as antioxidant enzymes and thus may inhibit lipid peroxidation. GR is stimulated by melatonin and is reportedly irreversibly inhibited by a number of oxygen radical generating systems.
|Synthetic peptide (2- Glutathione reductase protein) of GR (2- Glutathione reductase) protein.|
|PBS with 0.05% BSA and 0.05% sodium azide|
|GR, GRase, glutathione reductase, mitochondrial|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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