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GSR Rabbit anti-Human, Yeast, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523247

Catalog No. PIPA523247


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Description

Description

Glutathione reductase (GSR or GR) is a crucial flavoenzyme in the antioxidant defense system that maintains high levels of reduced glutathione in the cytosol. It belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family and is a flavoprotein homodimer of two equal subunits with one mole of noncovalently bound FAD in each subunit. GR reduces glutathione disulphide (GSSG) to the sulfhydryl form (GSH) which is an important cellular oxidant and is used by glutathione peroxidase to detoxify hydrogen peroxide. Apart from NADPH, GR also uses FAD as a cofactor for the process. In sperm, GR and glutathione peroxidase function as antioxidant enzymes and thus may inhibit lipid peroxidation. GR is stimulated by melatonin and is reportedly irreversibly inhibited by a number of oxygen radical generating systems.
Specifications

Specifications

GSR
Polyclonal
Unconjugated
GSR
Liquid
GSR
Synthetic peptide (2- Glutathione reductase protein) of GR (2- Glutathione reductase) protein.
Protein A
RUO
Antibody
Polyclonal
Human, Yeast
Western Blot
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
P00390
GR, GRase, glutathione reductase, mitochondrial
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
2936
Documents
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