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Gram Negative Endotoxin Mouse anti-Bacteria, Clone: IVEC9-220.1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA110692

Catalog No. 01-671-923


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Description

Description

MA1-10692 detects Endotoxin from K. pneumoniae, E. aerogenes, S. marcescens, P. mirabilis, P. vulgaris, A. calcoaceticus, and Ps. aeruginosa samples. MA1-10692 has been successfully used in ELISA applications. The MA1-10692 immunogen is E. coli serotypes: O:111, B4 J5.

Endotoxins are part of the outer membrane of the cell wall of gram-negative bacteria. Endotoxins are invariably associated with gram-negative bacteria whether the organisms are pathogens or not. Although the term "endotoxin" is occasionally used to refer to any cell-associated bacterial toxin, it is properly reserved to refer to the lipopolysaccharide complex associated with the outer membrane of gram-negative bacteria such as E. coli, Salmonella, Shigella, Pseudomonas, Neisseria, Haemophilus, and other leading pathogens. The biological activity of endotoxin is associated with the lipopolysaccharide (LPS). Toxicity is associated with the lipid component (Lipid A) and immunogenicity is associated with the polysaccharide components. The cell wall antigens (O antigens) of gram-negative bacteria are components of LPS. LPS elicits a variety of inflammatory responses in an animal. Because it activates complement by the alternative (properdin) pathway, it is often part of the pathology of gram-negative bacterial infections.
Specifications

Specifications

Gram Negative Endotoxin
Monoclonal
1.0 mg/mL
PBS with no preservative; pH 7.4
Mouse
IgM
500 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
Bacteria
ELISA
IVEC9-220.1
Unconjugated
Liquid
E. coli serotypes: O:111, B4 J5.
Purified
RUO
Antibody
Monoclonal
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