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Granzyme B Mouse anti-Human, PE-CF594, Clone: GB11, BD
Mouse Monoclonal Antibody
Supplier: BD Biosciences 562462
Description
Monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. Antibody was conjugated with Horizon™ PE-CF594 under optimum conditions, and unconjugated antibody and free PE-CF594 were removed. Granzyme B is stored in the granules of cytotoxic T lymphocytes and NK cells along with the pore-forming protein perforin. Granzyme B acts on specific substrates including caspase-3, -7, -9, and -10 which in turn give rise to enzymes that mediate apoptosis.
Host Species: Mouse
Clone: GB11
Isotype: IgG1, κ
Species Reactivity: Human
Immunogen: Human Granzyme B
- Involved in the hydrolysis of extracellular matrix components
- PE-CF594 can be excited by the blue (488nm), green (532nm) and yellow-green (561nm) lasers and can be detected with the same filter set as PE-Texas Red
Intracellular Staining, Flow Cytometry
Specifications
Granzyme B | |
Monoclonal | |
5μL | |
GZMB; Granzyme-2; CCPI; CGL1; CSPB; CTLA1; CTSGL1; GRB; HLP; SECT | |
Mouse | |
Affinity Purified | |
RUO | |
Human | |
IgG1 κ |
Flow Cytometry | |
GB11 | |
PE-CF594 | |
Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
Human Granzyme B | |
50 Tests | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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