Granzyme K Mouse anti-Human, Clone: GM24C3, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA117753
This antibody recognizes native Granzyme K protein expressed in transfected mammalian cells.Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
|cDNA encoding human Granzyme K|
|ELISA, Flow Cytometry|
|PBS with no preservative; pH 7.2|
|Store at 4°C short term. For long term storage, Store at -20°C, avoiding freeze/thaw cycles.|
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