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Granzyme K Mouse anti-Human, Clone: GM26E7, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA117754

Catalog No. 01-670-167


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Description

Description

This antibody recognizes native Granzyme K protein expressed in transfected mammalian cells. This antibody can be used in a Sandwich ELISA as a capture antibody with Product No. MA1-17755 as a detection antibody.

Granzyme K (GrK) belongs to a family of trypsin-like serine proteases localised in the cytotoxic granules of activated T cells and NK cells. It encodes a 28 kDa serine protease whose gene is located on chromosome 5q11-12 close to the granzyme A-encoding gene. Like granzyme A, it has a trypsin-like specifity cleaving at the basic residues arginine and lysine. Granzyme K triggers rapid cell death independently of caspase activation with single-stranded DNA nicks and is primarily expressed in thymus, lung, spleen and peripheral blood leukocytes.
Specifications

Specifications

Granzyme K
Monoclonal
Unconjugated
GZMK
Liquid
GZMK
cDNA encoding human Granzyme K
Protein G
RUO
Antibody
Monoclonal
Human
ELISA, Flow Cytometry
GM26E7
PBS with no preservative; pH 7.2
P49863
GrK
Mouse
IgG1
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
3003
Documents
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