GRB2-related adaptor protein, Mouse, Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human GRAP protein.

Manufacturer:  Abnova Corporation H00010750B01

Catalog No. 89-007-048

Description

This gene encodes a member of the GRB2/Sem5/Drk family. This member functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. [provided by RefSeq

Sequence: MESVALYSFQATESDELAFNKGDTLKILNMEDDQNWYKAELRGVEGFIPKNYIRVKPHPWYSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKYFLWEEKFNSLNELVDFYRTTTIAKKRQIFLRDEEPLLKSPGACFAQAQFDFSAQDPSQLSFRRGDIIEVLERPDPHWWRGRSCGRVGFFPRSYVQPVHL

Specifications

• Antigen: GRB2-related adaptor protein
• Conjugate: Unconjugated
• Formulation: No additive
• Gene Accession No.: NM_006613
• Gene Alias: MGC64880
• Host Species: Mouse
• Quantity: 50 uL
• Research Discipline: Membrane Receptors
• Whole Molecule: Y
• Monoclonal or Polyclonal: Polyclonal
• Target Species: Human

• Applications: Western Blot
• Description: Mouse polyclonal antibody raised against a full-length human GRAP protein.
• Gene: GRAP
• Format: Serum
• Gene Symbols: GRAP
• Immunogen: GRAP (NP_006604, 1 a.a. ~ 217 a.a) full-length human protein.
• Regulatory Status: RUO
• Storage Requirements: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Primary or Secondary: Primary
• Gene ID (Entrez): 10750