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GRASP1 Rabbit anti-Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14662

Catalog No. PA14662


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Description

Description

This antibody is predicted to react with bovine, canine, human and mouse based on 100% sequence homology. This antibody is specific for the ~95 kDa GRASP protein.

PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).
Specifications

Specifications

GRASP1
Polyclonal
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Q9JHZ4
GRIP-associated protein
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
116493
Western Blot
Unconjugated
Gripap1
Liquid
GRIPAP1
Synthetic peptide corresponding to the C-terminal region of rat GRIPAP1 conjugated to KLH
Affinity chromatography
RUO
Antibody
Polyclonal
Rat
Documents
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