GRB2 Goat anti-Human, Mouse, Porcine, Rat, Polyclonal, Invitrogen
Goat Polyclonal Antibody
Manufacturer: Invitrogen PA19051
This antibody is expected to recognize both reported isoforms (NP_002077.1 and NP_987102.1). This antibody is predicted to react with bovine and canine based on sequence homology.GRB 2 protein contains one SH2 domain flanked on both sides by an SH3 domain. In response to EGF, GRB 2 binds, through its SH3 domains, to the guanine nucleotide exchange factor, Sos. The GRB 2 - Sos complex then binds the EGF receptor. These interactions play a critical role in the activation of the p21 ras signalling pathway.
|Synthetic peptide corresponding to the C terminus amino acids PRNYVTPVNRNV.|
|Antigen affinity chromatography|
|Human, Mouse, Porcine, Rat|
|Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot|
|TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3|
|P62993, Q60631, P62994|
|Growth Factor Receptor-bound protein 2; ASH; ASH protein; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; HT027; abundant SRC homology; epidermal growth factor|
|-20° C, Avoid Freeze/Thaw Cycles|
|100192436, 14784, 2885, 81504|
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