GluR4 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA524217
This antibody is predicted to react with non-human primate and rat based on sequence homology.Glutamate receptors are the predomit excitatoryneurotransmitter receptors in the mammalian brain and are activatedin a variety of normal neurophysiologic processes. These receptorsare heteromeric protein complexes composed of multiple subunits,arranged to form ligand-gated ion channels. The classification ofglutamate receptors is based on their activation by differentpharmacologic agonists. The subunit encoded by this gene belongs toa family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate)-sensitive glutamate receptors, and is subject to RNAediting (AGA->GGA; R->G). Alternative splicing of this gene resultsin transcript variants encoding different isoforms, which may varyin their signal transduction properties. Some haplotypes of thisgene show a positive association with schizophrenia.
|KLH conjugated synthetic peptide between 259-287 amino acids from the central region of human GRIA4|
|Antigen Affinity Chromatography, Protein A|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 0.09% sodium azide|
|GLUR4, GLUR4C, GLURD, GluA4, AMPA-selective glutamate receptor 4, gluR-4, gluR-D, glutamate receptor 4, glutamate receptor, ionotrophic, AMPA 4|
|-20° C, Avoid Freeze/Thaw Cycles|
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