Growth Hormone Sheep anti-Human, Polyclonal, Invitrogen
Sheep Polyclonal Antibody
Manufacturer: Invitrogen PA185519
Sheep anti Human growth hormone antibody recognizes human growth hormone. Growth hormone is a small peptide hormone released by the anterior pituitary under the control of the hypothalamus. It acts to control body growth and metabolic activity.Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.
|whole serum with 0.09% sodium azide|
|GH, GH-N, GHN, IGHD1B, hGH-N|
|ELISA, Radioimmune Assays|
|Purified native human growth hormone.|
|4°C or -20°C if preferred|
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