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GRP94 Rabbit anti-Equine, Human, Mouse, Non-human primate, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523177

Catalog No. PIPA523177


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Description

Description

GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.
Specifications

Specifications

GRP94
Polyclonal
Unconjugated
HSP90B1
Liquid
HSP90B1
Synthetic peptide (592 AKEGVKFDESEKTKESREA 610) of GRP94 protein.
Protein G
RUO
Antibody
Polyclonal
Equine, Human, Mouse, Non-human primate
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
0.5 mg/mL
PBS with 0.2% gelatin and 0.05% sodium azide
P14625, P08113
ECGP; GP96; GRP94; TRA1; 94 kDa glucose-regulated protein; GRP-94; Tumor rejection antigen-1; endoplasmin; endothelial cell (HBMEC) glycoprotein; glucose regulated protein; 94 kDa; gp96 homolog; heat shock protein 90 kDa beta member 1; tumor rejection antigen 1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
100033933, 22027, 7184
Documents
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