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GRPR Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA526791

Catalog No. PIPA526791


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Description

Description

This antibody is predicted to react with mouse and rat based on sequence homology.

Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
Specifications

Specifications

GRPR
Polyclonal
PBS with 0.09% sodium azide
P30550
GRP-R, GRP-preferring bombesin receptor
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2925
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
GRPR
Liquid
GRPR
KLH conjugated synthetic peptide between 123-152 amino acids from the central region of human GRPR
Antigen Affinity Chromatography, Protein A
RUO
Antibody
Polyclonal
Human
Documents
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