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GSK3 alpha/beta, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA121047

Catalog No. PIPA121047

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase, a key enzyme in glycogen metabolism. Since then, it has been shown to be involved in the regulation of a diverse array of cellular functions, including protein synthesis, cell proliferation, cell differentiation, microtubule assembly/disassembly, and apoptosis. GSK3s substrate specificity is unique in that phosphorylation of substrate only occurs if a phosphoserine or phosphotyrosine is present four residues C terminal to the site of GSK phosphorylation.

PA1-21047 detects GSK3 alpha/beta in Human, Mouse, Rat and Non-human primate samples.PA1-21047 has been successfully used in Immunohistochemistry (Paraffin) procedures.PA1-21047 immunogen corresponds to synthetic peptide (Human) (C-terminal).
Specifications

Specifications

GSK3 alpha + beta
Polyclonal
PBS with 1% BSA and 0.1% sodium azide; pH 7.4
P49840, P49841, Q2NL51, Q9WV60, P18265, P18266
Gsk3a, Gsk3b, Glycogen Synthase Kinase Alpha/Beta, Glycogen Synthase Kinase Alpha, Glycogen Synthase Kinase Beta
Rabbit
IgG
7mL
4° C, do not freeze
Primary
2931, 2932
Immunohistochemistry (Paraffin)
Unconjugated
GSK3B
Purified
GSK3A, GSK3B
Synthetic peptide (Human) (C-terminal).
Purified
RUO
Antibody
Polyclonal
Human, Murine, Non-human Primate, Rat
Documents
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