GSK3 alpha/beta, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA121047
Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase, a key enzyme in glycogen metabolism. Since then, it has been shown to be involved in the regulation of a diverse array of cellular functions, including protein synthesis, cell proliferation, cell differentiation, microtubule assembly/disassembly, and apoptosis. GSK3s substrate specificity is unique in that phosphorylation of substrate only occurs if a phosphoserine or phosphotyrosine is present four residues C terminal to the site of GSK phosphorylation.PA1-21047 detects GSK3 alpha/beta in Human, Mouse, Rat and Non-human primate samples.PA1-21047 has been successfully used in Immunohistochemistry (Paraffin) procedures.PA1-21047 immunogen corresponds to synthetic peptide (Human) (C-terminal).
|GSK3 alpha + beta|
|PBS with 1% BSA and 0.1% sodium azide; pH 7.4|
|P49840, P49841, Q2NL51, Q9WV60, P18265, P18266|
|Gsk3a, Gsk3b, Glycogen Synthase Kinase Alpha/Beta, Glycogen Synthase Kinase Alpha, Glycogen Synthase Kinase Beta|
|4° C, do not freeze|
|Synthetic peptide (Human) (C-terminal).|
|Human, Murine, Non-human Primate, Rat|
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