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HAX-1 Mouse, Unlabeled, Clone: 52, BD

Mouse Monoclonal Antibody

$232.00 - $458.00

Specifications

Antigen HAX-1
Isotype IgG1
Immunogen Human HAX-1 aa. 10-148
Formulation Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
BDB610825
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BD Biosciences
610825
150μg
Each for $458.00
Add to cart
 
BDB610824
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BD Biosciences
610824
50μg
Each for $232.00
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Description

Description

Cell-cell interactions in the immune system, mediated by membrane-bound antigen receptors, trigger a cascade of signaling mechanisms collectively known as the T-cell response. Upon antigen binding, cellular tyrosine kinases are activated resulting in the phosphorylation of HS1 or Lck-binding protein 1 (LckBP1), which is involved in thymic negative selection. HS1 is one of the earliest intracellular proteins to be tyrosine phosphorylated in response to antigen-receptor cross-linking in T cells. HAX-1 (HS1-associated protein X-1) is a 35kDa protein found associated with HS1 by co-immunoprecipitation assays and the two-hybrid system. HAX-1 is ubiquitously expressed and localized in the mitochondria, endoplasmic reticulum, and the nuclear envelope. The HS1-HAX-1 complex may be critical for signal transduction pathways initiated by antigen presentation to T cells.

Immunofluorescence, Immunoprecipitation, Western Blotting

Specifications

Specifications

HAX-1
Human HAX-1 aa. 10-148
Unconjugated
Cell Biology
Mouse
Affinity Purified
Monoclonal
Store undiluted at -20°C.
IgG1
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Primary
Western Blot
RUO
52
250μg/mL
SDS
Product Certifications

For Research Use Only.

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