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HAX1 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA527592

Catalog No. PIPA527592


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Description

Description

PA5-27592 targets HAX1 in IF, IHC (P), and WB applications and shows reactivity with Human samples. The PA5-27592 immunogen is recombit fragment corresponding to a region within amino acids 1 and 279 of Human HAX1. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-domit polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

HAX1
Polyclonal
Unconjugated
HAX1
Liquid
HAX1
Recombit fragment corresponding to a region within amino acids 1 and 279 of Human HAX1
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 10% glycerol and 0.01% thimerosal; pH 7
O00165
HCLSBP1, HS1BP1, SCN3, HAX-1, HCLS1 (and PKD2) associated protein, HCLS1-associated protein X-1, HS1 binding protein, HS1-associating protein X-1, HS1-binding protein 1, HSP1BP-1
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
10456
Documents
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