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ITIH2 Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA11756

Catalog No. 01-674-570

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PA1-1756 detects HC2 from human and mouse samples. PA1-1756 has been successfully used in immunohistochemical staining of paraffin embedded tissue sections. The PA1-1756 immunogen is a synthetic peptide corresponding to residues E A N N L G L L D P N. This immunizing peptide (PEP-302) is available for neutralization and control experiments.

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.


Synthetic peptide corresponding to residues E A N N L G L L D P N.
Antigen affinity chromatography
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
1 mg/mL
PBS with 1mg/mL BSA and 0.05% sodium azide
P19823, Q61703
PSMA1, proteasome (prosome, macropain) subunit, alpha type, 1, 30 kDa prosomal protein, Macropain subunit C2
100 μg
-20° C, Avoid Freeze/Thaw Cycles
16425, 3698
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