HDAC5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA126366
PA1-26366 detects HDAC5 from human, mouse, and rat samples. PA1-26366 has been successfully used in immunoprecipitation, immunohistochemistry (P), and Western blot procedures. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|10014, 15184, 84580|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.2|
|FLJ90614, HD5, NY-CO-9|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok