Thermo Scientific Lab Vision Heat Shock Factor 1 (HSF1) Ab-1, Rat Monoclonal Antibody
Ensure accurate, reproducible results in western blotting, immunofluorescence, immunoprecipitation and gel supershift experiments.
Manufacturer: Thermo Scientific RT405P1
Ensure accurate, reproducible results in western blotting, immunofluorescence, immunoprecipitation and gel supershift experiments with Thermo Scientific Heat Shock Factor 1 (HSF1) Ab-1, Rat Monoclonal Antibody.HSF1 responds to cellular stress signals such as heat, heavy metals, and oxidative reagents; binds to heat shock response elements (HSEs) in the upstream region of heat shock gene and activates their transcription. Some laboratories have reported that the constitutive, non-DNA binding, monomeric form of inactive HSF1 is located in the cytoplasm. Upon activation, HSF1 is trimerized and is localized in nucleus where it binds DNA.
Host Species: Rat
Species Reactivity: Human, Mouse and Rat. Others not known.
Epitope: aa 425-439 of mouse HSF1
Immunogen: Recombinant mouse HSF1 protein (aa 1-503)
Molecular Weight: 70-85 kDa (depending upon the source and state of cells)
Positive Control: LS174T or MAD109 cells
Cellular Localization: Nuclear
- Western Blotting
- Immunoprecipitation (Native only)
- Gel Supershift
USA: RUO; Int'l: RUO
|Heat Shock Factor 1 (HSF1) Ab-1|
|Recombinant mouse HSF1 protein (aa1-503)|
|Immunoprecipitation, Western Blot|
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