Hemoglobin Mouse anti-Human, Clone: HB11-203.1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA110807
MA1-10807 detects Hemoglobin from human samples. This antibody does not detect bovine, chicken, equine, ovine, or porcine Hemoglobin. MA1-10807 has been successfully used in ELISA and Western blot applications. The MA1-10807 immunogen is purified human hemoglobin.The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5 ft.- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3 ft.. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5 ft. untranslated regions and the introns, but they differ significantly over the 3 ft. untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
|PBS with no preservative; pH 7.4|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|Purified human hemoglobin.|
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