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Hepatitis B Virus preS2 Rabbit anti-Virus, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA123356

Catalog No. PIPA123356


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Description

Description

PA1-23356 detects Hepatitis B Virus in Virus samples. PA1-23356 reacts with residues 132-145 [CQDPRVRGLYFPAGG] of the 42 kDa preS2 HBV protein. This sequence represents a B cell epitope. PA1-23356 has been successfully used in ELISA and Western Blot procedures. PA1-23356 immunogen corresponds to Hepatitis B Virus preS2 antigen. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze/thaw cycles.

The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. The HBV surface protein antigens (HBsAg) are comprised of three carboxyl co terminal HBs proteins termed large (LHBs), middle (MHBs) and small (SHBs, also called major) protein. LHBs and MHBs also share the highly hydrophobic, repetitive, membrane spanning S domain. In addition, MHBs has a 55 amino acid region called preS2. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.
Specifications

Specifications

Hepatitis B Virus preS2
Polyclonal
Unconjugated
Liquid
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
Virus
ELISA, Western Blot
1 mg/mL
PBS with 0.02% sodium azide
HepB; HBVgp4
Hepatitis B Virus preS2 antigen
Affinity chromatography
RUO
Antibody
Polyclonal
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