KCNH2 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA3860
PA3-860 detects HERG in human samples. PA3-860 has been used successfully in Western blot, immunfluorescence, and immunoprecipitation procedures. By Western blot this antibody detects the ~135 kDa and ~155 kDa forms of HERG. The PA3-860 immunogen corresponds to a cDNA fragment of HERG encoding 181 amino acid residues from the C-terminus.The human ether-a-go-go-related gene (HERG) encodes a voltage-gated potassium channel which has an important role in cardiac action potential repolarization in the mammalian heart. Mutations in HERG have been shown to cause chromosome 7-linked congenital long QT syndrome, a disorder associated with delayed cardiac repolarization, prolonged electrocardiographic QT intervals, and the development of ventricular arrhythmias. HERG channels are an important target for many drugs, and have emerged as a significant type of cardiac ion channel.
|whole serum with 0.05% sodium azide|
|human ether-a-go-go-related gene|
|Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot|
|Fusion Protein of HERG encoding 181 amino acid residues from the C-terminus.|
|-20° C, Avoid Freeze/Thaw Cycles|
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