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KCNH2 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA3860

Catalog No. PA3860


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Description

Description

PA3-860 detects HERG in human samples. PA3-860 has been used successfully in Western blot, immunfluorescence, and immunoprecipitation procedures. By Western blot this antibody detects the ~135 kDa and ~155 kDa forms of HERG. The PA3-860 immunogen corresponds to a cDNA fragment of HERG encoding 181 amino acid residues from the C-terminus.

The human ether-a-go-go-related gene (HERG) encodes a voltage-gated potassium channel which has an important role in cardiac action potential repolarization in the mammalian heart. Mutations in HERG have been shown to cause chromosome 7-linked congenital long QT syndrome, a disorder associated with delayed cardiac repolarization, prolonged electrocardiographic QT intervals, and the development of ventricular arrhythmias. HERG channels are an important target for many drugs, and have emerged as a significant type of cardiac ion channel.
Specifications

Specifications

KCNH2
Polyclonal
whole serum with 0.05% sodium azide
Q12809
human ether-a-go-go-related gene
Rabbit
IgG
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
KCNH2
Liquid
KCNH2
Fusion Protein of HERG encoding 181 amino acid residues from the C-terminus.
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
3757
Documents
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