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HES2 Rabbit anti-Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523479

Catalog No. PIPA523479


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Description

Description

Transcription factor HES-2, of the HES family of proteins, contains one basic helix-loop-helix (bHLH) domain and one orange domain. It is reported to express in vascular smooth muscle cells, and may have some role in their differentiation. Activation of Notch signaling pathway leads to activation of Hes family genes through the interaction between Notch intracellular domain and RBPSUH (CSL). Hes family proteins are mammalian homologs of Drosophila Hairy and Enhancer of split. The Hes family of transcriptional repressors are implicated in the cell fate determination of stem cells (or precursor cells) by suppressing the expression of tissue-specific transcriptional activators.
Specifications

Specifications

HES2
Polyclonal
Unconjugated
HES2
Liquid
HES2
Synthetic peptide (8 GDAAELRKSLKPLLEKRR 25) of HES-2 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Non-human primate, Rat
Immunohistochemistry (Paraffin)
0.5 mg/mL
PBS with 0.05% BSA and 0.05% sodium azide
Q9Y543, O54792, P35429
bHLHb40, class B basic helix-loop-helix protein 40, transcription factor HES-2
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
15206, 29567, 54626
Documents
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