HEXA Mouse anti-Human, Clone: 714729, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524335
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
|PBS with 5% trehalose and No Preservative|
|HEXA, TSD, beta-hexosaminidase subunit alpha, Beta-N-acetylhexosaminidase subunit alpha, EC 3.2.1, EC 22.214.171.124, hexosaminidase A (alpha polypeptide), Hexosaminidase subunit A, MGC99608, N-acetyl-beta-glucosaminidase subunit alpha, TSD|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Sf 21-derived recombit human Hexosaminidase A/HEXA Met1-Thr529|
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