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HIF3A Rabbit anti-Human, Mouse, Biotin, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA522747

Catalog No. PIPA522747

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In Western Blot analysis, a band is recognized at ~68 kDa representing HIF-3 alpha. Because a band at ~71 kDa is also seen in hypoxic samples,it is important to run a negative control lysate as well. Suggested positive control: Cos7 CoCl2-treated lysate.

Hypoxia-inducible factor (HIF) is one of the most important factors in the cellular response to hypoxia, transcriptionally activating genes encoding proteins that mediate adaptive responses to reduced oxygen availability. HIF is a heterodimer consisting of one of three subunits, HIF1 alpha, HIF2 alpha, or HIF3 alpha. HIF target genes play critical roles in metabolism, angiogenesis, cell proliferation and cell survival. HIF3 alpha protein is one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha 3 subunit lacks the transactivation domain found in factors containing either the alpha 1 or alpha 2 subunits. HIF3 alpha may be a marker for tumor growth and angiogenesis.


A synthetic peptide made to an internal region of the human HIF-3 alpha (within residues 250-350).
Protein G
Human, Mouse
Immunoprecipitation, Western Blot
24 mg/mL
PBS with no preservative
Q9Y2N7, Q0VBL6
HIF-3A, IPAS, MOP7, PASD7, bHLHe17, HIF3-alpha-1, PAS domain-containing protein 7, basic-helix-loop-helix-PAS protein MOP7, class E basic helix-loop-helix protein 17, hypoxia-inducible factor 3-alpha, inhibitory PAS domain protein, member of PAS protein 7
100 μL
4° C, store in dark
53417, 64344
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