Kininogen Heavy Chain Mouse anti-Human, Clone: 2B5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA110832
MA1-10832 detects High MW Kininogen, heavy chain, from human samples. MA1-10832 has been successfully used in ELISA and Western blot applications. The MA1-10832 immunogen is purified high molecular weight kininogen.This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.
|Kininogen Heavy Chain|
|PBS with no preservative; pH 7.4|
|HMWK, Williams-Fitzgerald-Flaujeac factor, Fitzgerald factor, HMWK-kallikrein factor|
|-20° C, Avoid Freeze/Thaw Cycles|
|ELISA, Western Blot|
|Purified high molecular weight kininogen.|
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