Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

HIPK3 Rabbit anti-Canine, Human, Mouse, Non-human primate, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA523171

Catalog No. PIPA523171


Add to cart

Description

Description

HIPK3, a mammalian homolog of YAK1, is a novel 130 kDa nuclear co-factor that belongs to the HIPK protein family. Members of this family localize to nuclear speckles and consist of an evolutionarily conserved protein kinase domain and a homeoprotein-interacting domain. Physiological functions of HIPK3 have been predicted in different cell signaling pathways including transcriptional co-repression, cell differentiation, growth suppression, steroidogenesis and apoptosis. Research suggests that HIPK3 is a FADD-interacting protein kinase found to phosphorylate FADD and promote its binding to Fas, thereby inhibiting Fas-mediated Jun NH (2)-terminal kinase activation. HIPK3 also has been found to phosphorylate JNK and c-JUN, thus enhancing SF-1 activity for CYP11A1 transcription. HIPK3 plays a key role in cAMP-dependant signaling pathway.
Specifications

Specifications

HIPK3
Polyclonal
Unconjugated
HIPK3
Liquid
HIPK3
Synthetic peptide (875 DTDEEETSQRHSLR 888) of HIPK3 protein.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Canine, Human, Mouse, Non-human primate, Rat
Immunohistochemistry (Paraffin), Western Blot
1.0 mg/mL
PBS with 0.05% sodium azide
Q9H422, Q9ERH7, O88850
RP1-8L15.1, DYRK6, FIST3, PKY, YAK1, ANPK, FIST, androgen receptor-interacting nuclear protein kinase, fas-interacting serine/threonine-protein kinase, homeodomain-interacting protein kinase 3, homolog of protein kinase YAK1
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
10114, 15259, 475947, 83617
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit