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Kallikrein 11 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA14312

Catalog No. PA14312



Description

Description

PA1-4312 detects the Hippostatin/KLK11 protein in human, mouse, and rat samples. PA1-4312 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~38 kDa protein representing KLK11 in LNCaP cell lysate. PA1-4312 immunizing peptide corresponds to amino acid residues 68-82 of the 35 kDa human hippostasin/KLK11protein. There is 86% sequence identity to mouse and rat.

Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
Specifications

Specifications

Kallikrein 11
Polyclonal
Unconjugated
KLK11
Liquid
KLK11
Synthetic peptide: Y(68) I V H L G Q H N L Q K E E G(82)
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Western Blot
1 mg/mL
PBS with 0.02% sodium azide
Q9UBX7, Q9QYN3
Trypsin-like protease
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
11012, 292849, 56538
Documents
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