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Kallikrein 11 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA14312
PA1-4312 detects the Hippostatin/KLK11 protein in human, mouse, and rat samples. PA1-4312 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~38 kDa protein representing KLK11 in LNCaP cell lysate. PA1-4312 immunizing peptide corresponds to amino acid residues 68-82 of the 35 kDa human hippostasin/KLK11protein. There is 86% sequence identity to mouse and rat.Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of KLK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.
|Synthetic peptide: Y(68) I V H L G Q H N L Q K E E G(82)|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|PBS with 0.02% sodium azide|
|-20° C, Avoid Freeze/Thaw Cycles|
|11012, 292849, 56538|
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